I use the combined FO3/FNV NMC texture pack at the lightest setting. My computer has plenty of VRAM to handle (AMD 7970), but I don't really see a difference between the highest and the lowest settings haha.
As for ENB, I use a modified E ENB. Essentially I turned on original post processing and object processing (I think) and turned everything off except Depth of Field and lowered the ambient lighting, especially indoors. Because of this, IMODS like night vision work and the performance hit is minimal. I can upload the enb config files if you like.
For weather, I only use TTW Fellout as it's stable, and looks good. No rain, but I can survive. ;)
Oh EDIT: Doing the Victory Rifle next. 'Murica
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