I started out in vault 101 and when I lvl'd up I chose the "educated" perk that has 10 ranks. It's the perk that lets you choose an extra s.p.e.c.i.a.l attribute point each time. When I got to the 8 rank I took the train to New Vegas and woke up in Doc Mitchells house without any problems. When Doc wanted me to use the vigor machine I had to minus my 8 perk points that I put into the educated perk in order to get the vigor to work so I could leave his house. Which isn't that big of deal but I lose those points and the perk doesn't reset because I checked, it doesn't give them back to me. I guess you can only have a certain amount of attrib points when you leave doc's house. So I end up with only 2 educated perks instead of the 10 I should have for the game.
You guys have made a real stable mod here. I couldn't run MMM in the past it would ctd my rig every time there was more than 1 mob on my screen. Now I play with AWOP and MMM and it chuggs a little but I dont crash woohoo! I am just amazed at how well the game plays now. I think after having both games since release I can finally play it to the end without frustration and headaches :)
If you want I can post my loadorder and such if you want them.