I downloaded the 2.2a installer and installation itself seemed to go off without a hitch. But when I run the game it has an issue right away. As it plays the New Vegas start-up and music I realize my mouse isn't registering. Then when the Ranger background for the menu appears, no menu pops up. Hence I'm stuck at what should be the start-up menu. I double and triple checked the load order of the esm files and it's in the exact order.
Any idea how to fix this?