The heap you're referring to in the nvsrini?
I just did, and it seemed to make a big improvement. Still a little crashy but this combined with roy's suggestion makes this pretty close to playable (crashes are more along the lines of 30 mins to an hour, with some real trouble areas being meagaton and scrapyard, crashes more frequent, around 15 mins)
I know its a lot of mods, I'm expecting to pry some off before making an honest go at the game, but figured I'd "start" with "Man if i could run all this i'd be in hog heaven" :P