first things first
move TTWFixes.esm directly after TaleOfTwoWastelands.esm
go into your install dir and make a folder called "backups" and move every single plugin that you are NOT using into it. The game indexes them anyways and that can be a major cause of issues.
If you have stuff from TTW fixes in your personal or bashed patch (or any other mods), load up your patches in FNVEdit right click them and select "sort masters" after you move/alter things in your load order. They will appear orange in Wrye when the masters are out of order. Other plugins may also have this issue, but generally it can be a guideline to what order your plugins should be in.
I will report this issue with TTW Fixes to loot author.

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